Lionheart Health Advances in $101M XPRIZE Healthspan Competition
Lionheart Health, Inc., an Orange County, California-based biotechnology company, has been named one of the 40 semi-finalists in the prestigious $101M XPRIZE Healthspan Competition held at the Longevity Investors Summit in New York City. The competition, which drew 596 teams from 53 countries, aims to accelerate breakthroughs in healthspan longevity.
The XPRIZE mission is to inspire and empower humanity to achieve breakthroughs that accelerate an abundant and equitable future for all. Lionheart Health’s selection as a semi-finalist earned them a $250,000 award. To win the competition, teams must demonstrate that their treatment can restore muscle, cognitive, and immune function by a minimum of 10 years, with a goal of 20 years, in individuals aged 50-80 within a year or less.
Lionheart Health has developed a patented technology platform that uses precise bioelectric signaling sequences to control the release or regeneration-promoting proteins from tissues and cells. The company has also created bioelectrically enhanced biologics, including Klotho-expressing stem cells suspended in a proprietary nutrient hydrogel. Recent studies have shown that the Klotho protein plays a significant role in aging and longevity, extending lifespan and improving cognitive function in animal models.
“Our solution harnesses the body’s natural healing processes to promote regeneration and renewal,” stated Dr. Leslie Miller, Lionheart Health’s Chief Medical Officer. The company has demonstrated its ability to control regenerative protein expressions in animal studies and over 300 patients in pilot clinical studies.
In the next phase, Lionheart Health must demonstrate its healthspan extension protocol in an IRB-approved, one-year clinical study supervised by a data safety monitoring board with patient consent. “Advancing as an XPRIZE Healthspan top 40 finalist is a proud moment for Lionheart Health and our entire team,” said Howard Leonhardt, Lead Inventor of the Lionheart Health technology platform and Founder, Executive Chairman, and co-CEO.
Lionheart Health is working in partnership with BioLeonhardt Whole Body and other partners to develop a whole-body regeneration chamber that combines AI, advanced robotics, stem cells, and regeneration-promoting growth factors. The company plans to open 124 MedSpa clinics specializing in medical aesthetics and physician-directed healthspan longevity protocols over the next 60 months.

About Lionheart Health, Inc.: Lionheart Health, Inc. is a 2022 spinout of Leonhardt Ventures LLC, a venture creation house and invention factory focused on organ regeneration and accelerating recovery. With over 500 patent claims related to organ regeneration and healthspan longevity, Lionheart Health is poised to make significant advancements in the field.