Physical Activity Improves Mental Health in Women with Chronic Pelvic Pain
New York, NY – A recent study from Mount Sinai Hospital provides encouraging evidence that regular physical activity can significantly benefit the mental health of women grappling with chronic pelvic pain disorders (CPPDs). The research, published in the Journal of Pain Research, highlights the potential of exercise as a valuable tool in managing the challenges associated with conditions like endometriosis and uterine fibroids.
The study found a clear association between moderate-to-vigorous physical activity and improved mental well-being in the women studied. The research team, led by Dr. Ipek Ensari at the Icahn School of Medicine, used mobile health technology to track participants’ activity and mental health over a 14-week period.
The study found that in women with chronic pelvic pain disorders, more weekly moderate-to-vigorous intensity physical activity was associated with better mental health and physical function. Higher pain levels were linked to worse mental health but not strongly connected to physical activity. Credit: Journal of Pain Research (2025). DOI: 10.2147/JPR.S499102
“Chronic pelvic pain disorders are incredibly complex and burdensome for those affected, yet we still have very few effective treatment strategies,” explained Dr. Ensari. “Our research suggests that physical activity could be an important tool for improving mental health in these patients, offering them a proactive way to enhance their well-being.”
The study involved 76 women with CPPDs who used a smartphone app and Fitbit devices to record data. This allowed researchers to analyze how movement patterns related to changes in mental health over time. A key finding was that the benefits of exercise appeared to develop gradually rather than provide instantaneous relief.
“We were particularly intrigued to find that the positive effects of exercise seem to lag by a few days, meaning the mental health benefits may build up gradually,” noted Dr. Ensari. This insight is crucial for both patients and healthcare providers, emphasizing the need for consistent physical activity.
Beyond its direct implications for patient care, the study underscores the growing role of artificial intelligence and mobile health technologies in managing chronic diseases. “This study showcases the power of wearable technology and AI-driven analysis to uncover valuable insights about health and behavior in real time,” said Dr. Girish N. Nadkarni, Chair of the Windreich Department of Artificial Intelligence and Human Health at the Icahn School of Medicine.
The researchers are clear that physical activity shouldn’t replace medical treatment, but it can be a valuable addition. Future research will explore how different types and intensity levels of exercise affect pain, fatigue, and mental health, with the goal of creating personalized interventions that use wearable technology and mobile apps.
Reference: Leventhal, E. et al. (2025). Trajectories of mHealth-Tracked Mental Health and Their Predictors in Female Chronic Pelvic Pain Disorders, Journal of Pain Research. DOI: 10.2147/JPR.S499102
